MedComic

Basal Cell Carcinoma vs. Squamous Cell Carcinoma

Jorge Muniz ·
Educational medical illustration comparing basal cell carcinoma (BCC) presenting as a pearly papule with telangiectasias and squamous cell carcinoma (SCC) presenting as a hyperkeratotic lesion with crusting, including diagnosis and treatment approaches
Illustrated guide comparing basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) — the two most common non-melanoma skin cancers — including clinical features, risk factors, and treatment. Proprietary medical illustration by Jorge Muniz, PA-C.

Basal Cell Carcinoma (BCC)

  • Most common type of skin cancer
  • Occurs in sun-exposed areas
  • Presents as a "pearly" papule or nodule that grows slowly
  • The lesion tends to develop a shiny appearance with telangiectasias
  • Features an umbilicated center or ulcer

Squamous Cell Carcinoma (SCC)

  • May occur on any skin surface, but is most commonly seen on sun-exposed areas
  • May arise from actinic keratoses
  • Occurs at sites of chronic wounds or scarring
  • More common and more aggressive in immunosuppressed or transplant patients
  • Variable appearance
  • Usually characterized as a hyperkeratotic lesion with crusting and ulceration

Diagnosis and Treatment

  • For both BCC and SCC, biopsy is indicated for diagnosis
  • Lesions are typically treated with surgical excision, cryotherapy, electrodessication, or topical chemotherapy

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