Tetralogy of Fallot
Jorge Muniz
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- Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect
- The main components include pulmonary stenosis, right ventricular hypertrophy, an overriding aorta, and a ventricular septal defect
- A mnemonic to recall these features is PROV
- The four components of TOF is thought to result from a single defect: anterior malposition of the infundibular septum
- Hypoxemic spells, also known as "Tet spells," represent a hallmark of severe TOF
- Chest radiographs often show a boot-shaped heart, characterized by right ventricular hypertrophy with upturning of the apex
- Echocardiography is the diagnostic study of choice
- Treatment typically involves a modified Blalock-Taussig procedure or definitive repair